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The vision of the Clemons lab is to improve outcomes for gastro-oesophageal cancer patients through better treatment selection and development of new treatment strategies. These goals are built on a foundation of an in depth... Read more

The Robert Ramsay laboratory specialises in transcriptional control, stem cell biology and models of colorectal cancer (CRC), peroneal cancers (for example, anal and penile SCCs) and their metastasis. We were the first in... Read more

With the recognition over the last 10 years that cancer is a genetic disease, the approach to diagnosis and classification of cancer and stratifying patients for treatment has radically changed. The use of biomarkers that define... Read more

The research focuses on understanding how cells of the tumour microenvironment can contribute to the progression of cancer either by promoting resistance to existing drugs or through enhancing metastatic spread. We are using... Read more

Barrett’s oesophagus is a metaplasia, acquired as a consequence of chronic acid and bile reflux, where the normal squamous epithelium is replaced by an intestinal-type columnar epithelium. Clinically, Barrett’s oesophagus is... Read more

Harnessing a patient's immune system to attack cancer is the most exciting recent breakthrough in cancer treatment. One of the central mechanisms of action for immunotherapy is reactivation of key killer immune cells, called CD8+... Read more